This study is required by regulatory agencies and used to evaluate the release of active molecules by the finished product, for topical use or for application on mucous tissue.

The results are used to evaluate or compare the efficacy of the active released through the skin for solid, semi-solid or liquid formulations, as well as patch-release devices.

Franz cell system – simulates how a human in vivo permeation of a certain active would be, by using pig’s ear skin.